Arteriolar reactivity and capillarization in chronically stimulated rat limb skeletal muscle post-MI
نویسندگان
چکیده
منابع مشابه
Arteriolar reactivity and capillarization in chronically stimulated rat limb skeletal muscle post-MI.
The purpose of this study was to assess whether electrical stimulation-induced increases in muscular activity could improve capillary supply and correct previously documented abnormal vasodilator and vasoconstrictor responses of arterioles in limb skeletal muscle post-myocardial infarction (MI). Extensor digitorum longus (EDL) muscle from rats with surgically induced MI ( approximately 30% of t...
متن کاملTime course of collagen and decorin changes in rat cardiac and skeletal muscle post-MI.
We examined the temporal relationship between messages (type I and type III mRNAs) for the principal fibrillar procollagens and subsequent collagen accretion, cross-linking, and decorin expression in the left ventricle (LV) postmyocardial infarction (post-MI). We sought to determine 1) what role the proteoglycan decorin plays in extracellular matrix (ECM) remodeling known to take place as a con...
متن کاملIncreased skeletal muscle capillarization enhances insulin sensitivity.
Increased skeletal muscle capillarization is associated with improved glucose tolerance and insulin sensitivity. However, a possible causal relationship has not previously been identified. Therefore, we investigated whether increased skeletal muscle capillarization increases insulin sensitivity. Skeletal muscle-specific angiogenesis was induced by adding the α1-adrenergic receptor antagonist pr...
متن کاملSkeletal muscle arteriolar reactivity in SS.BN13 consomic rats and Dahl salt-sensitive rats.
Previous studies have demonstrated that angiotensin II is a crucial factor in maintaining normal vascular reactivity. In this study, we tested the hypothesis that altered reactivity to vasoactive stimuli in Dahl salt-sensitive (S) rats on a high salt diet could be prevented by introgression of chromosome 13 from the normotensive Brown Norway strain, which carries a normally functioning renin ge...
متن کاملIntegration of skeletal muscle resistance arteriolar reactivity for perfusion responses in the metabolic syndrome.
Previous study suggests that with evolution of the metabolic syndrome, patterns of arteriolar reactivity are profoundly altered and may constrain functional hyperemia. This study investigated interactions between parameters of vascular reactivity at two levels of resistance arterioles in obese Zucker rats (OZR), translating these observations into perfusion regulation for in situ skeletal muscl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 1999
ISSN: 8750-7587,1522-1601
DOI: 10.1152/jappl.1999.87.6.2259